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Different analgesic effects of adenosine between postoperative and neuropathic pain

BACKGROUND: Adenosine is an endogenous neuromodulator in both the peripheral and central nervous systems. Adenosine inhibits pain signals by hyperpolarizing neuronal membrane. METHODS: To clarify the effects of adenosine on pain signals, we tested intrathecal adenosine injection in two neuropathic p...

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Detalles Bibliográficos
Autores principales: Yamaoka, Gotaro, Horiuchi, Hideki, Morino, Tadao, Miura, Hiromasa, Ogata, Tadanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553403/
https://www.ncbi.nlm.nih.gov/pubmed/22996813
http://dx.doi.org/10.1007/s00776-012-0302-0