PDK1 inhibition is a novel therapeutic target in multiple myeloma

BACKGROUND: Cancer cells utilise the glycolytic pathway even when adequate oxygen is present, a phenomenon known as the Warburg effect. We examined whether this system is operative in multiple myeloma (MM) cells and whether glycolysis inhibition is a potential therapeutic modality. METHODS: The MM c...

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Detalles Bibliográficos
Autores principales: Fujiwara, S, Kawano, Y, Yuki, H, Okuno, Y, Nosaka, K, Mitsuya, H, Hata, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553526/
https://www.ncbi.nlm.nih.gov/pubmed/23321518
http://dx.doi.org/10.1038/bjc.2012.527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553526/
https://www.ncbi.nlm.nih.gov/pubmed/23321518
http://dx.doi.org/10.1038/bjc.2012.527

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