Altered TUBB3 expression contributes to the epothilone response of mitotic cells

BACKGROUND: Epothilones are a novel group of microtubule (mt) targeting cancer drugs that bind to the β-subunit of the αβ-tubulin dimer. Epothilones inhibit cell proliferation and induce cell death by interfering with the normal mt function. In this study, we examined the consequences of altered exp...

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Detalles Bibliográficos
Autores principales: Narvi, E, Jaakkola, K, Winsel, S, Oetken-Lindholm, C, Halonen, P, Kallio, L, Kallio, M J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553534/
https://www.ncbi.nlm.nih.gov/pubmed/23321512
http://dx.doi.org/10.1038/bjc.2012.553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553534/
https://www.ncbi.nlm.nih.gov/pubmed/23321512
http://dx.doi.org/10.1038/bjc.2012.553

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