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Crystal structure and functional characterization of the human RBM25 PWI domain and its flanking basic region

Human RBM25 (RNA-binding motif protein 25) is a novel splicing factor that contains a PWI domain, a newly identified RNA/DNA-binding domain, and regulates Bcl-x pre-mRNA alternative splicing. The flanking basic region has been suggested to serve as a co-operative partner of the PWI domain in the bin...

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Detalles Bibliográficos
Autores principales: Gong, Deshun, Yang, Fan, Li, Fudong, Qian, Dandan, Wu, Minhao, Shao, Zhenhua, Wu, Mian, Wu, Jihui, Shi, Yunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553564/
https://www.ncbi.nlm.nih.gov/pubmed/23190262
http://dx.doi.org/10.1042/BJ20121382