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Enzyme-inhibitor-like tuning of Ca(2+) channel connectivity with calmodulin
Ca(2+) channels and calmodulin are two prominent signaling hubs(1) that synergistically impact functions as diverse as cardiac excitability(2), synaptic plasticity(3), and gene transcription(4). It is thereby fitting that these hubs are in some sense coordinated, as the opening of Ca(V)1-2 Ca(2+) ch...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553577/ https://www.ncbi.nlm.nih.gov/pubmed/20139964 http://dx.doi.org/10.1038/nature08766 |