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Enzyme-inhibitor-like tuning of Ca(2+) channel connectivity with calmodulin

Ca(2+) channels and calmodulin are two prominent signaling hubs(1) that synergistically impact functions as diverse as cardiac excitability(2), synaptic plasticity(3), and gene transcription(4). It is thereby fitting that these hubs are in some sense coordinated, as the opening of Ca(V)1-2 Ca(2+) ch...

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Detalles Bibliográficos
Autores principales: Liu, Xiaodong, Yang, Philemon S., Yang, Wanjun, Yue, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553577/
https://www.ncbi.nlm.nih.gov/pubmed/20139964
http://dx.doi.org/10.1038/nature08766