Cargando…

Multifunctional protein APPL2 contributes to survival of human glioma cells

Some endocytic proteins have recently been shown to play a role in tumorigenesis. In this study, we demonstrate that APPL2, an adapter protein with known endocytic functions, is upregulated in 40% cases of glioblastoma multiforme, the most common and aggressive cancer of the central nervous system....

Descripción completa

Detalles Bibliográficos
Autores principales: Pyrzynska, Beata, Banach-Orlowska, Magdalena, Teperek-Tkacz, Marta, Miekus, Katarzyna, Drabik, Grazyna, Majka, Marcin, Miaczynska, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553582/
https://www.ncbi.nlm.nih.gov/pubmed/22989406
http://dx.doi.org/10.1016/j.molonc.2012.08.003