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High-resolution transcriptome and genome-wide dynamics of RNA polymerase and NusA in Mycobacterium tuberculosis

To construct a regulatory map of the genome of the human pathogen, Mycobacterium tuberculosis, we applied two complementary high-resolution approaches: strand-specific RNA-seq, to survey the global transcriptome, and ChIP-seq, to monitor the genome-wide dynamics of RNA polymerase (RNAP) and the anti...

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Detalles Bibliográficos
Autores principales: Uplekar, Swapna, Rougemont, Jacques, Cole, Stewart T., Sala, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553938/
https://www.ncbi.nlm.nih.gov/pubmed/23222129
http://dx.doi.org/10.1093/nar/gks1260