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Phosphoinositide 3-kinase beta controls replication factor C assembly and function

Genomic integrity is preserved by the action of protein complexes that control DNA homeostasis. These include the sliding clamps, trimeric protein rings that are arranged around DNA by clamp loaders. Replication factor C (RFC) is the clamp loader for proliferating cell nuclear antigen, which acts on...

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Detalles Bibliográficos
Autores principales: Redondo-Muñoz, Javier, Josefa Rodríguez, María, Silió, Virginia, Pérez-García, Vicente, María Valpuesta, José, Carrera, Ana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553946/
https://www.ncbi.nlm.nih.gov/pubmed/23175608
http://dx.doi.org/10.1093/nar/gks1095