DNA cleavage by Type ISP Restriction–Modification enzymes is initially targeted to the 3′-5′ strand

The mechanism by which a double-stranded DNA break is produced following collision of two translocating Type I Restriction–Modification enzymes is not fully understood. Here, we demonstrate that the related Type ISP Restriction–Modification enzymes LlaGI and LlaBIII can cooperate to cleave DNA follo...

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Detalles Bibliográficos
Autores principales: van Aelst, Kara, Šišáková, Eva, Szczelkun, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553963/
https://www.ncbi.nlm.nih.gov/pubmed/23221632
http://dx.doi.org/10.1093/nar/gks1210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553963/
https://www.ncbi.nlm.nih.gov/pubmed/23221632
http://dx.doi.org/10.1093/nar/gks1210

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