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Steric antisense inhibition of AMPA receptor Q/R editing reveals tight coupling to intronic editing sites and splicing

Adenosine-to-Inosine (A-to-I) RNA editing is a post-transcriptional mechanism, evolved to diversify the transcriptome in metazoa. In addition to wide-spread editing in non-coding regions protein recoding by RNA editing allows for fine tuning of protein function. Functional consequences are only know...

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Detalles Bibliográficos
Autores principales: Penn, Andrew C., Balik, Ales, Greger, Ingo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553965/
https://www.ncbi.nlm.nih.gov/pubmed/23172291
http://dx.doi.org/10.1093/nar/gks1044