Selection of tRNA charging quality control mechanisms that increase mistranslation of the genetic code

Mistranslation can follow two events during protein synthesis: production of non-cognate amino acid:transfer RNA (tRNA) pairs by aminoacyl-tRNA synthetases (aaRSs) and inaccurate selection of aminoacyl-tRNAs by the ribosome. Many aaRSs actively edit non-cognate amino acids, but editing mechanisms ar...

Descripción completa

Detalles Bibliográficos
Autores principales: Yadavalli, Srujana S., Ibba, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553970/
https://www.ncbi.nlm.nih.gov/pubmed/23222133
http://dx.doi.org/10.1093/nar/gks1240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553970/
https://www.ncbi.nlm.nih.gov/pubmed/23222133
http://dx.doi.org/10.1093/nar/gks1240

Ejemplares similares