Novel Smad proteins localize to IR-induced double-strand breaks: interplay between TGFβ and ATM pathways

Cellular damage from ionizing radiation (IR) is in part due to DNA damage and reactive oxygen species, which activate DNA damage response (DDR) and cytokine signaling pathways, including the ataxia telangiectasia mutated (ATM) and transforming growth factor (TGF)β/Smad pathways. Using classic double...

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Detalles Bibliográficos
Autores principales: Wang, Minli, Saha, Janapriya, Hada, Megumi, Anderson, Jennifer A., Pluth, Janice M., O’Neill, Peter, Cucinotta, Francis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553971/
https://www.ncbi.nlm.nih.gov/pubmed/23221633
http://dx.doi.org/10.1093/nar/gks1038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553971/
https://www.ncbi.nlm.nih.gov/pubmed/23221633
http://dx.doi.org/10.1093/nar/gks1038

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