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A versatile cis-blocking and trans-activation strategy for ribozyme characterization

Synthetic RNA control devices that use ribozymes as gene-regulatory components have been applied to controlling cellular behaviors in response to environmental signals. Quantitative measurement of the in vitro cleavage rate constants associated with ribozyme-based devices is essential for advancing...

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Detalles Bibliográficos
Autores principales: Kennedy, Andrew B., Liang, Joe C., Smolke, Christina D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553993/
https://www.ncbi.nlm.nih.gov/pubmed/23155065
http://dx.doi.org/10.1093/nar/gks1036