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Extended Family History of Type 1 Diabetes and Phenotype and Genotype of Newly Diagnosed Children

OBJECTIVE: To determine the frequency of newly diagnosed diabetic children with first- and second-degree relatives affected by type 1 diabetes and to characterize the effects of this positive family history on clinical markers, signs of β-cell autoimmunity, and HLA genotype in the index case. RESEAR...

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Detalles Bibliográficos
Autores principales: Parkkola, Anna, Härkönen, Taina, Ryhänen, Samppa J., Ilonen, Jorma, Knip, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554291/
https://www.ncbi.nlm.nih.gov/pubmed/23033245
http://dx.doi.org/10.2337/dc12-0445