Cargando…

Constitutive STAT3 Phosphorylation Contributes to Skeletal Muscle Insulin Resistance in Type 2 Diabetes

Signal transducer and activator of transcription 3 (STAT3) is involved in cytokine- and nutrient-induced insulin resistance. The role of STAT3 in the development of skeletal muscle insulin resistance and type 2 diabetes (T2D) pathogenesis is incompletely defined. We tested the hypothesis that STAT3...

Descripción completa

Detalles Bibliográficos
Autores principales: Mashili, Fredirick, Chibalin, Alexander V., Krook, Anna, Zierath, Juleen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554355/
https://www.ncbi.nlm.nih.gov/pubmed/23043161
http://dx.doi.org/10.2337/db12-0337