Cargando…
Constitutive STAT3 Phosphorylation Contributes to Skeletal Muscle Insulin Resistance in Type 2 Diabetes
Signal transducer and activator of transcription 3 (STAT3) is involved in cytokine- and nutrient-induced insulin resistance. The role of STAT3 in the development of skeletal muscle insulin resistance and type 2 diabetes (T2D) pathogenesis is incompletely defined. We tested the hypothesis that STAT3...
Autores principales: | Mashili, Fredirick, Chibalin, Alexander V., Krook, Anna, Zierath, Juleen R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554355/ https://www.ncbi.nlm.nih.gov/pubmed/23043161 http://dx.doi.org/10.2337/db12-0337 |
Ejemplares similares
-
siRNA-Mediated Reduction of Inhibitor of Nuclear Factor-κB Kinase Prevents Tumor Necrosis Factor-α–Induced Insulin Resistance in Human Skeletal Muscle
por: Austin, Reginald L., et al.
Publicado: (2008) -
Muscle-Specific IRS-1 Ser→Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle
por: Morino, Katsutaro, et al.
Publicado: (2008) -
Bimodal Effect on Pancreatic β-Cells of Secretory Products From Normal or Insulin-Resistant Human Skeletal Muscle
por: Bouzakri, Karim, et al.
Publicado: (2011) -
Dual Role of Interleukin-6 in Regulating Insulin Sensitivity in Murine Skeletal Muscle
por: Nieto-Vazquez, Iria, et al.
Publicado: (2008) -
Skeletal Muscle Protein Tyrosine Phosphatase 1B Regulates Insulin Sensitivity in African Americans
por: Stull, April J., et al.
Publicado: (2012)