β-Cell Failure in Type 2 Diabetes: A Case of Asking Too Much of Too Few?

The islet in type 2 diabetes (T2DM) is characterized by a deficit in β-cells, increased β-cell apoptosis, and extracellular amyloid deposits derived from islet amyloid polypeptide (IAPP). In the absence of longitudinal studies, it is unknown if the low β-cell mass in T2DM precedes diabetes onset (is...

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Detalles Bibliográficos
Autores principales: Costes, Safia, Langen, Ralf, Gurlo, Tatyana, Matveyenko, Aleksey V., Butler, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Perspectives in Diabetes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554362/
https://www.ncbi.nlm.nih.gov/pubmed/23349537
http://dx.doi.org/10.2337/db12-1326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554362/
https://www.ncbi.nlm.nih.gov/pubmed/23349537
http://dx.doi.org/10.2337/db12-1326

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