PAQR3 Modulates Insulin Signaling by Shunting Phosphoinositide 3-Kinase p110α to the Golgi Apparatus

Phosphoinositide 3-kinase (PI3K) mediates insulin actions by relaying signals from insulin receptors (IRs) to downstream targets. The p110α catalytic subunit of class IA PI3K is the primary insulin-responsive PI3K implicated in insulin signaling. We demonstrate here a new mode of spatial regulation...

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Detalles Bibliográficos
Autores principales: Wang, Xiao, Wang, Lingdi, Zhu, Lu, Pan, Yi, Xiao, Fei, Liu, Weizhong, Wang, Zhenzhen, Guo, Feifan, Liu, Yong, Thomas, Walter G., Chen, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554364/
https://www.ncbi.nlm.nih.gov/pubmed/23086038
http://dx.doi.org/10.2337/db12-0244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554364/
https://www.ncbi.nlm.nih.gov/pubmed/23086038
http://dx.doi.org/10.2337/db12-0244

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