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Neuronal Androgen Receptor Regulates Insulin Sensitivity via Suppression of Hypothalamic NF-κB–Mediated PTP1B Expression

Clinical investigations highlight the increased incidence of metabolic syndrome in prostate cancer (PCa) patients receiving androgen deprivation therapy (ADT). Studies using global androgen receptor (AR) knockout mice demonstrate that AR deficiency results in the development of insulin resistance in...

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Detalles Bibliográficos
Autores principales: Yu, I-Chen, Lin, Hung-Yun, Liu, Ning-Chun, Sparks, Janet D., Yeh, Shuyuan, Fang, Lei-Ya, Chen, Lumin, Chang, Chawnshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554386/
https://www.ncbi.nlm.nih.gov/pubmed/23139353
http://dx.doi.org/10.2337/db12-0135