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Neuronal Androgen Receptor Regulates Insulin Sensitivity via Suppression of Hypothalamic NF-κB–Mediated PTP1B Expression
Clinical investigations highlight the increased incidence of metabolic syndrome in prostate cancer (PCa) patients receiving androgen deprivation therapy (ADT). Studies using global androgen receptor (AR) knockout mice demonstrate that AR deficiency results in the development of insulin resistance in...
Autores principales: | Yu, I-Chen, Lin, Hung-Yun, Liu, Ning-Chun, Sparks, Janet D., Yeh, Shuyuan, Fang, Lei-Ya, Chen, Lumin, Chang, Chawnshang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554386/ https://www.ncbi.nlm.nih.gov/pubmed/23139353 http://dx.doi.org/10.2337/db12-0135 |
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