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Divide and Conquer: Functional Segregation of Synaptic Inputs by Astrocytic Microdomains Could Alleviate Paroxysmal Activity Following Brain Trauma

Traumatic brain injury often leads to epileptic seizures. Among other factors, homeostatic synaptic plasticity (HSP) mediates posttraumatic epileptogenesis through unbalanced synaptic scaling, partially compensating for the trauma-incurred loss of neural excitability. HSP is mediated in part by tumo...

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Detalles Bibliográficos
Autores principales: Volman, Vladislav, Bazhenov, Maxim, Sejnowski, Terrence J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554537/
https://www.ncbi.nlm.nih.gov/pubmed/23357960
http://dx.doi.org/10.1371/journal.pcbi.1002856