A Hybrid Likelihood Model for Sequence-Based Disease Association Studies

In the past few years, case-control studies of common diseases have shifted their focus from single genes to whole exomes. New sequencing technologies now routinely detect hundreds of thousands of sequence variants in a single study, many of which are rare or even novel. The limitation of classical...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yun-Ching, Carter, Hannah, Parla, Jennifer, Kramer, Melissa, Goes, Fernando S., Pirooznia, Mehdi, Zandi, Peter P., McCombie, W. Richard, Potash, James B., Karchin, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554549/
https://www.ncbi.nlm.nih.gov/pubmed/23358228
http://dx.doi.org/10.1371/journal.pgen.1003224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554549/
https://www.ncbi.nlm.nih.gov/pubmed/23358228
http://dx.doi.org/10.1371/journal.pgen.1003224

Ejemplares similares