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The Role of Potassium Channel Activation in Celecoxib-Induced Analgesic Action

BACKGROUND AND PURPOSE: Celecoxib (CXB) is a widely prescribed COX-2 inhibitor used clinically to treat pain and inflammation. Recently, COX-2 independent mechanisms have been described to be the targets of CXB. For instance, ion channels such as the voltage-gated sodium channel, L-type calcium chan...

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Detalles Bibliográficos
Autores principales: Mi, Yao, Zhang, Xuan, Zhang, Fan, Qi, Jinlong, Gao, Haixia, Huang, Dongyang, Li, Li, Zhang, Hailin, Du, Xiaona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554616/
https://www.ncbi.nlm.nih.gov/pubmed/23358696
http://dx.doi.org/10.1371/journal.pone.0054797