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Cellular Robustness Conferred by Genetic Crosstalk Underlies Resistance against Chemotherapeutic Drug Doxorubicin in Fission Yeast

Doxorubicin is an anthracycline antibiotic that is among one of the most commonly used chemotherapeutic agents in the clinical setting. The usage of doxorubicin is faced with many problems including severe side effects and chemoresistance. To overcome these challenges, it is important to gain an und...

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Detalles Bibliográficos
Autores principales: Tay, Zoey, Eng, Ru Jun, Sajiki, Kenichi, Lim, Kim Kiat, Tang, Ming Yi, Yanagida, Mitsuhiro, Chen, Ee Sin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554685/
https://www.ncbi.nlm.nih.gov/pubmed/23365689
http://dx.doi.org/10.1371/journal.pone.0055041