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Potassium and Ionic Strength Effects on the Conformational and Thermal Stability of Two Aldehyde Dehydrogenases Reveal Structural and Functional Roles of K(+)-Binding Sites

Many aldehyde dehydrogenases (ALDHs) have potential potassium-binding sites of as yet unknown structural or functional roles. To explore possible K(+)-specific effects, we performed comparative structural studies on the tetrameric betaine aldehyde dehydrogenase from Pseudomonas aeruginosa (PaBADH) a...

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Detalles Bibliográficos
Autores principales: Garza-Ramos, Georgina, Mújica-Jiménez, Carlos, Muñoz-Clares, Rosario A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554688/
https://www.ncbi.nlm.nih.gov/pubmed/23365686
http://dx.doi.org/10.1371/journal.pone.0054899