The Functional DRD3 Ser9Gly Polymorphism (rs6280) Is Pleiotropic, Affecting Reward as Well as Movement

Abnormalities of motivation and behavior in the context of reward are a fundamental component of addiction and mood disorders. Here we test the effect of a functional missense mutation in the dopamine 3 receptor (DRD3) gene (ser9gly, rs6280) on reward-associated dopamine (DA) release in the striatum...

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Detalles Bibliográficos
Autores principales: Savitz, Jonathan, Hodgkinson, Colin A., Martin-Soelch, Chantal, Shen, Pei-Hong, Szczepanik, Joanna, Nugent, Allison, Herscovitch, Peter, Grace, Anthony A., Goldman, David, Drevets, Wayne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554713/
https://www.ncbi.nlm.nih.gov/pubmed/23365649
http://dx.doi.org/10.1371/journal.pone.0054108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554713/
https://www.ncbi.nlm.nih.gov/pubmed/23365649
http://dx.doi.org/10.1371/journal.pone.0054108

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