SB225002 Promotes Mitotic Catastrophe in Chemo-Sensitive and -Resistant Ovarian Cancer Cells Independent of p53 Status In Vitro

Recent evidence indicates that CXCR2 signaling is crucial for cancer progression, and its antagonist SB225002 induces apoptosis in Wilms’ tumor cells. Here, we investigated the effect of SB225002 on cell cycle progression and apoptosis induction in vitro, using CDDP-sensitive and -resistant OVCA cel...

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Detalles Bibliográficos
Autores principales: Du, Meirong, Qiu, Qing, Gruslin, Andree, Gordon, John, He, Miao, Chan, Chi Chung, Li, Dajin, Tsang, Benjamin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554720/
https://www.ncbi.nlm.nih.gov/pubmed/23359652
http://dx.doi.org/10.1371/journal.pone.0054572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554720/
https://www.ncbi.nlm.nih.gov/pubmed/23359652
http://dx.doi.org/10.1371/journal.pone.0054572

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