Genistein Sensitizes Bladder Cancer Cells to HCPT Treatment In Vitro and In Vivo via ATM/NF-κB/IKK Pathway-Induced Apoptosis

Bladder cancer is the most common malignant urological disease in China. Hydroxycamptothecin (HCPT) is a DNA topoisomerase I inhibitor, which has been utilized in chemotherapy for bladder cancer for nearly 40 years. Previous research has demonstrated that the isoflavone, genistein, can sensitize mul...

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Detalles Bibliográficos
Autores principales: Wang, Yong, Wang, He, Zhang, Wei, Shao, Chen, Xu, Peng, Shi, Chang Hong, Shi, Jian Guo, Li, Yu Mei, Fu, Qiang, Xue, Wei, Lei, Yong Hua, Gao, Jing Yu, Wang, Juan Ying, Gao, Xiao Ping, Li, Jin Qing, Yuan, Jian Lin, Zhang, Yun Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554754/
https://www.ncbi.nlm.nih.gov/pubmed/23365634
http://dx.doi.org/10.1371/journal.pone.0050175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554754/
https://www.ncbi.nlm.nih.gov/pubmed/23365634
http://dx.doi.org/10.1371/journal.pone.0050175

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