Pentosan Polysulfate: A Novel Therapy for the Mucopolysaccharidoses

BACKGROUND: Pentosan polysulfate (PPS) is an FDA-approved, oral medication with anti-inflammatory and pro-chondrogenic properties. We have previously shown that animal models of the mucopolysaccharidoses (MPS) exhibit significant inflammatory disease, contributing to cartilage degeneration. Enzyme r...

Descripción completa

Detalles Bibliográficos
Autores principales: Schuchman, Edward H., Ge, Yi, Lai, Alon, Borisov, Yury, Faillace, Meghan, Eliyahu, Efrat, He, Xingxuan, Iatridis, James, Vlassara, Helen, Striker, Gary, Simonaro, Calogera M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554761/
https://www.ncbi.nlm.nih.gov/pubmed/23365668
http://dx.doi.org/10.1371/journal.pone.0054459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554761/
https://www.ncbi.nlm.nih.gov/pubmed/23365668
http://dx.doi.org/10.1371/journal.pone.0054459

Ejemplares similares