Cargando…

Pentosan Polysulfate: A Novel Therapy for the Mucopolysaccharidoses

BACKGROUND: Pentosan polysulfate (PPS) is an FDA-approved, oral medication with anti-inflammatory and pro-chondrogenic properties. We have previously shown that animal models of the mucopolysaccharidoses (MPS) exhibit significant inflammatory disease, contributing to cartilage degeneration. Enzyme r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schuchman, Edward H., Ge, Yi, Lai, Alon, Borisov, Yury, Faillace, Meghan, Eliyahu, Efrat, He, Xingxuan, Iatridis, James, Vlassara, Helen, Striker, Gary, Simonaro, Calogera M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554761/ https://www.ncbi.nlm.nih.gov/pubmed/23365668 http://dx.doi.org/10.1371/journal.pone.0054459

Ejemplares similares

Dose Responsive Effects of Subcutaneous Pentosan Polysulfate Injection in Mucopolysaccharidosis Type VI Rats and Comparison to Oral Treatment
por: Frohbergh, Michael, et al.
Publicado: (2014)

Safety Study of Sodium Pentosan Polysulfate for Adult Patients with Mucopolysaccharidosis Type II
por: Orii, Kenji, et al.
Publicado: (2019)

Pentosan Polysulfate: Oral Versus Subcutaneous Injection in Mucopolysaccharidosis Type I Dogs
por: Simonaro, Calogera M., et al.
Publicado: (2016)

Efficacy of pentosan polysulfate in in vitro models of lysosomal storage disorders: Fabry and Gaucher Disease
por: Crivaro, Andrea N., et al.
Publicado: (2019)

Maculopathy caused by pentosan polysulfate
por: Rosenberg, Daniel, et al.
Publicado: (2021)

Visual Function in Pentosan Polysulfate Sodium Maculopathy
por: Lyons, Riley J., et al.
Publicado: (2020)

Potential Anti-SARS-CoV-2 Activity of Pentosan Polysulfate and Mucopolysaccharide Polysulfate
por: Zhang, Fuming, et al.
Publicado: (2022)

Maculopathie causée par le polysulfate de pentosan
por: Rosenberg, Daniel, et al.
Publicado: (2021)

Anti-TNF-Alpha Therapy Enhances the Effects of Enzyme Replacement Therapy in Rats with Mucopolysaccharidosis Type VI
por: Eliyahu, Efrat, et al.
Publicado: (2011)

Pentosan polysulfate regulates hepcidin expression in native Mongolian horses
por: WIJEKOON, Suranji, et al.
Publicado: (2022)

Pentosan Polysulfate Affords Pleotropic Protection to Multiple Cells and Tissues
por: Smith, Margaret M., et al.
Publicado: (2023)

Acid Ceramidase Protects Against Hepatic Ischemia/Reperfusion Injury by Modulating Sphingolipid Metabolism and Reducing Inflammation and Oxidative Stress
por: Jiang, Yuan, et al.
Publicado: (2021)

A case of pentosan polysulfate maculopathy originally diagnosed as stargardt disease
por: Vora, Robin A., et al.
Publicado: (2020)

Maculopathy Secondary to Pentosan Polysulfate Use: A Single-Center Experience
por: Kalbag, Neil S, et al.
Publicado: (2021)

Type 3 macular neovascularization in a patient with pentosan polysulfate maculopathy
por: Bousquet, Elodie, et al.
Publicado: (2022)

Acute and severe haemorrhage following pentosan polysulfate injection in a Cornish Rex
por: Tong, Miranda X, et al.
Publicado: (2021)

Pentosan Polysulfate Sodium-Associated Pigmentary Retinopathy: Risk Factors and Fundus Findings
por: Leung, Ella H, et al.
Publicado: (2021)

Efficacy of Pentosan Polysulfate Treatment in Patients with Interstitial Cystitis/Bladder Pain Syndrome
por: Arıkan, Mehmet Gürkan, et al.
Publicado: (2023)

Effects of pentosan polysulfate and polysulfated glycosaminoglycan on chondrogenesis of canine bone marrow-derived mesenchymal stem cells in alginate and micromass culture
por: BWALYA, Eugene C., et al.
Publicado: (2017)

Sodium pentosan polysulfate resulted in cartilage improvement in knee osteoarthritis - An open clinical trial-
por: Kumagai, Kenji, et al.
Publicado: (2010)

Postmortem findings in a case of variant Creutzfeldt-Jakob disease treated with intraventricular pentosan polysulfate
por: Newman, P K, et al.
Publicado: (2014)

The effect of Hydrodistension in combination with Pentosan Polysulfate on treatment outcomes and compliance in the treatment of bladder pain syndrome
por: Simsir, Adnan, et al.
Publicado: (2019)

Xylan Prebiotics and the Gut Microbiome Promote Health and Wellbeing: Potential Novel Roles for Pentosan Polysulfate
por: Smith, Margaret M., et al.
Publicado: (2022)

An unusual case of rapid resolution of bilateral vitelliform deposits after discontinuation of pentosan polysulfate sodium
por: Kalaw, Fritz Gerald P., et al.
Publicado: (2023)

Acid Ceramidase Maintains the Chondrogenic Phenotype of Expanded Primary Chondrocytes and Improves the Chondrogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells
por: Simonaro, Calogera M., et al.
Publicado: (2013)

Inhibitory effects of sodium pentosan polysulfate on formation and function of osteoclasts derived from canine bone marrow
por: Wijekoon, H. M. Suranji, et al.
Publicado: (2018)

Broad Th2 neutralization and anti‐inflammatory action of pentosan polysulfate sodium in experimental allergic rhinitis
por: Sanden, Caroline, et al.
Publicado: (2017)

Pentosan polysulfate promotes proliferation and chondrogenic differentiation of adult human bone marrow-derived mesenchymal precursor cells
por: Ghosh, Peter, et al.
Publicado: (2010)

Identification of Patients with Pentosan Polysulfate Sodium-Associated Maculopathy through Screening of the Electronic Medical Record at an Academic Center
por: Higgins, Kendall, et al.
Publicado: (2020)

Pentosan polysulfate regulates hepcidin 1-facilitated formation and function of osteoclast derived from canine bone marrow
por: Wijekoon, Suranji, et al.
Publicado: (2022)

Transient Postoperative Hemorrhage from Elbow Arthroscopy Portals following Intra-Articular Pentosan Polysulfate Sodium Injection
por: Parker, Lindsay A., et al.
Publicado: (2022)

Role of oral pentosan polysulfate in Bacillus Calmette–Guérin therapy in patients with non-muscle-invasive bladder cancer
por: Lee, Ho Yeon, et al.
Publicado: (2022)

Pentosan Polysulfate Inhibits Attachment and Infection by SARS-CoV-2 In Vitro: Insights into Structural Requirements for Binding
por: Bertini, Sabrina, et al.
Publicado: (2022)

The effect of pentosan polysulfate sodium for improving dyslipidaemia and knee pain in people with knee osteoarthritis: A pilot study
por: Liu, Xiaoqian, et al.
Publicado: (2023)

Safety and efficacy of pentosan polysulfate in patients with bladder pain syndrome/interstitial cystitis: a multicenter, double–blind, placebo–controlled, randomized study
por: Kasyan, George, et al.
Publicado: (2021)

New paradigms for the treatment of lysosomal storage diseases: targeting the endocannabinoid system as a therapeutic strategy
por: Schuchman, Edward H., et al.
Publicado: (2021)

Enzyme replacement therapy for Farber disease: Proof-of-concept studies in cells and mice
por: He, Xingxuan, et al.
Publicado: (2017)

Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex
por: Troeberg, Linda, et al.
Publicado: (2012)

Effects of pentosan polysulfate on cell proliferation, cell cycle progression and cyclin-dependent kinases expression in canine articular chondrocytes
por: AKARAPHUTIPORN, Ekkapol, et al.
Publicado: (2020)

Pentosan polysulfate sodium prevents functional decline in chikungunya infected mice by modulating growth factor signalling and lymphocyte activation
por: Rudd, Penny A., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ug8cu6e9l3plgkmd4f4fkjmt90