Random Parameter Sampling of a Generic Three-Tier MAPK Cascade Model Reveals Major Factors Affecting Its Versatile Dynamics

The mitogen-activated protein kinase (MAPK) pathway is considered to be a central block in many biological signaling networks. Despite the common core cascade structure, the activation of MAPK in different biological systems can exhibit different types of dynamic behaviors. Computer modeling may hel...

Descripción completa

Detalles Bibliográficos
Autores principales: Mai, Zhongxing, Liu, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554771/
https://www.ncbi.nlm.nih.gov/pubmed/23365667
http://dx.doi.org/10.1371/journal.pone.0054441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554771/
https://www.ncbi.nlm.nih.gov/pubmed/23365667
http://dx.doi.org/10.1371/journal.pone.0054441

Ejemplares similares