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Stability of Zinc Finger Nuclease Protein Is Enhanced by the Proteasome Inhibitor MG132
BACKGROUND: Zinc finger nucleases (ZFNs) are powerful tools for gene therapy and genetic engineering. The characterization of ZFN protein stability and the development of simple methods to improve ZFN function would facilitate the application of this promising technology. However, the factors that a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554775/ https://www.ncbi.nlm.nih.gov/pubmed/23365657 http://dx.doi.org/10.1371/journal.pone.0054282 |