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IRGM Variants and Susceptibility to Inflammatory Bowel Disease in the German Population

BACKGROUND & AIMS: Genome-wide association studies identified the autophagy gene IRGM to be strongly associated with Crohn's disease (CD) but its impact in ulcerative colitis (UC), its phenotypic effects and potential epistatic interactions with other IBD susceptibility genes are less clear...

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Detalles Bibliográficos
Autores principales: Glas, Jürgen, Seiderer, Julia, Bues, Stephanie, Stallhofer, Johannes, Fries, Christoph, Olszak, Torsten, Tsekeri, Eleni, Wetzke, Martin, Beigel, Florian, Steib, Christian, Friedrich, Matthias, Göke, Burkhard, Diegelmann, Julia, Czamara, Darina, Brand, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554777/
https://www.ncbi.nlm.nih.gov/pubmed/23365659
http://dx.doi.org/10.1371/journal.pone.0054338