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Sodium channel β2 subunit promotes filopodia-like processes and expansion of the dendritic tree in developing rat hippocampal neurons

The β2 auxiliary subunit of voltage-gated sodium channels (VGSCs) appears at early stages of brain development. It is abundantly expressed in the mammalian central nervous system where it forms complexes with different channel isoforms, including Na(v)1.2. From the structural point of view, β2 is a...

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Detalles Bibliográficos
Autores principales: Maschietto, Marta, Girardi, Stefano, Dal Maschio, Marco, Scorzeto, Michele, Vassanelli, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555079/
https://www.ncbi.nlm.nih.gov/pubmed/23355803
http://dx.doi.org/10.3389/fncel.2013.00002