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Re-thinking cell cycle regulators: the cross-talk with metabolism

Analysis of genetically engineered mice deficient in cell cycle regulators, including E2F1, cdk4, and pRB, showed that the major phenotypes are metabolic perturbations. These key cell cycle regulators contribute to lipid synthesis, glucose production, insulin secretion, and glycolytic metabolism. It...

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Detalles Bibliográficos
Autor principal: Fajas, Lluis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555080/
https://www.ncbi.nlm.nih.gov/pubmed/23355973
http://dx.doi.org/10.3389/fonc.2013.00004