Cargando…

The long-range interaction landscape of gene promoters

The vast non-coding portion of the human genome is awash in functional elements and disease-causing regulatory variants. The principles defining the relationships between these elements and distal target genes remain unknown. Promoters and distal elements can engage in looping interactions that have...

Descripción completa

Detalles Bibliográficos
Autores principales: Sanyal, Amartya, Lajoie, Bryan, Jain, Gaurav, Dekker, Job
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555147/
https://www.ncbi.nlm.nih.gov/pubmed/22955621
http://dx.doi.org/10.1038/nature11279