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The long-range interaction landscape of gene promoters
The vast non-coding portion of the human genome is awash in functional elements and disease-causing regulatory variants. The principles defining the relationships between these elements and distal target genes remain unknown. Promoters and distal elements can engage in looping interactions that have...
Autores principales: | Sanyal, Amartya, Lajoie, Bryan, Jain, Gaurav, Dekker, Job |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555147/ https://www.ncbi.nlm.nih.gov/pubmed/22955621 http://dx.doi.org/10.1038/nature11279 |
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