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New models of pulmonary hypertension based on VEGF receptor blockade-induced endothelial cell apoptosis

In spite of treatment, severe angioproliferative pulmonary arterial hypertension (PAH) remains a disease characterized by great morbidity and shortened survival. New treatment strategies for patients with PAH are needed, and after drug development, preclinical studies are best conducted in animal mo...

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Detalles Bibliográficos
Autores principales: Nicolls, Mark R., Mizuno, Shiro, Taraseviciene-Stewart, Laima, Farkas, Laszlo, Drake, Jennnifer I., Al Husseini, Aysar, Gomez-Arroyo, Jose G., Voelkel, Norbert F., Bogaard, Herman J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555413/
https://www.ncbi.nlm.nih.gov/pubmed/23372927
http://dx.doi.org/10.4103/2045-8932.105031