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Transforming growth factor-β inhibition and endothelin receptor blockade in rats with monocrotaline-induced pulmonary hypertension

Transforming growth factor-β (TGF-β) inhibition is an investigational therapy for pulmonary arterial hypertension with promising results in experimental studies. The present work compared this approach with endothelin-receptor blockade and evaluated the effects of combined administration. Pulmonary...

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Detalles Bibliográficos
Autores principales: Megalou, Aikaterini J., Glava, Chryssoula, Vilaeti, Agapi D., Oikonomidis, Dimitrios L., Baltogiannis, Giannis G., Papalois, Apostolos, Vlahos, Antonios P., Kolettis, Theofilos M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555416/
https://www.ncbi.nlm.nih.gov/pubmed/23372930
http://dx.doi.org/10.4103/2045-8932.105034