Associated inflammation or increased flow-mediated shear stress, but not pressure alone, disrupts endothelial caveolin-1 in infants with pulmonary hypertension

Endothelial caveolin-1 loss is an important feature of pulmonary hypertension (PH); the rescue of caveolin-1 abrogates experimental PH. Recent studies in human PH suggest that the endothelial caveolin-1 loss is followed by an enhanced expression of caveolin-1 in smooth muscle cells (SMC) with subseq...

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Detalles Bibliográficos
Autores principales: Dereddy, Narendra, Huang, Jing, Erb, Markus, Guzel, Sibel, Wolk, John H, Sett, Suvro S, Gewitz, Michael H, Mathew, Rajamma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555420/
https://www.ncbi.nlm.nih.gov/pubmed/23372934
http://dx.doi.org/10.4103/2045-8932.105038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555420/
https://www.ncbi.nlm.nih.gov/pubmed/23372934
http://dx.doi.org/10.4103/2045-8932.105038

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