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Peroxisome Proliferator-Activated Receptor-γ Agonist 15d-Prostaglandin J(2) Mediates Neuronal Autophagy after Cerebral Ischemia-Reperfusion Injury

Peroxisome proliferator-activated receptor-γ (PPAR-γ) has recently emerged as potential therapeutic agents for cerebral ischemia-reperfusion (I/R) injury because of anti-neuronal apoptotic actions. However, whether PPAR-γ activation mediates neuronal autophagy in such conditions remains unclear. The...

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Detalles Bibliográficos
Autores principales: Xu, Feng, Li, Jian, Ni, Wei, Shen, Yi-wen, Zhang, Xiao-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555818/
https://www.ncbi.nlm.nih.gov/pubmed/23372817
http://dx.doi.org/10.1371/journal.pone.0055080