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Engineering Foot-and-Mouth Disease Viruses with Improved Growth Properties for Vaccine Development

BACKGROUND: No licensed vaccine is currently available against serotype A foot-and-mouth disease (FMD) in China, despite the isolation of A/WH/CHA/09 in 2009, partly because this strain does not replicate well in baby hamster kidney (BHK) cells. METHODOLOGY/PRINCIPAL FINDINGS: A novel plasmid-based...

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Detalles Bibliográficos
Autores principales: Zheng, Haixue, Guo, Jianhong, Jin, Ye, Yang, Fan, He, Jijun, Lv, Lv, Zhang, Kesan, Wu, Qiong, Liu, Xiangtao, Cai, Xuepeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555929/
https://www.ncbi.nlm.nih.gov/pubmed/23372840
http://dx.doi.org/10.1371/journal.pone.0055228