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Paramecium BBS genes are key to presence of channels in Cilia

BACKGROUND: Changes in genes coding for ciliary proteins contribute to complex human syndromes called ciliopathies, such as Bardet-Biedl Syndrome (BBS). We used the model organism Paramecium to focus on ciliary ion channels that affect the beat form and sensory function of motile cilia and evaluate...

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Detalles Bibliográficos
Autores principales: Valentine, Megan Smith, Rajendran, Anbazhagan, Yano, Junji, Weeraratne, S Dilhan, Beisson, Janine, Cohen, Jean, Koll, France, Van Houten, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556005/
https://www.ncbi.nlm.nih.gov/pubmed/23351336
http://dx.doi.org/10.1186/2046-2530-1-16