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Overexpression of aldo-keto-reductase in azole-resistant clinical isolates of Candida glabrata determined by cDNA-AFLP

BACKGROUND: Candida glabrata causes significant medical problems in immunocompromised patients. Many strains of this yeast are intrinsically resistant to azole antifungal agents, and treatment is problematic, leading to high morbidity and mortality rates in immunosuppressed individuals. The primary...

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Detalles Bibliográficos
Autores principales: Farahyar, Shirin, Zaini, Farideh, Kordbacheh, Parivash, Rezaie, Sassan, Safara, Mahin, Raoofian, Reza, Heidari, Mansour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556022/
https://www.ncbi.nlm.nih.gov/pubmed/23351326
http://dx.doi.org/10.1186/2008-2231-21-1