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Atad3 Function Is Essential for Early Post-Implantation Development in the Mouse

The mitochondrial AAA+-ATPase ATAD3 is implicated in the regulation of mitochondrial and ER dynamics and was shown to be necessary for larval development in Caenorhabditis elegans. In order to elucidate the relevance of ATAD3 for mammalian development, the phenotype of an Atad3 deficient mouse line...

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Detalles Bibliográficos
Autores principales: Goller, Tobias, Seibold, Ursula K., Kremmer, Elisabeth, Voos, Wolfgang, Kolanus, Waldemar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556029/
https://www.ncbi.nlm.nih.gov/pubmed/23372768
http://dx.doi.org/10.1371/journal.pone.0054799