Positive allosteric modulation of TRPV1 as a novel analgesic mechanism

BACKGROUND: The prevalence of long-term opiate use in treating chronic non-cancer pain is increasing, and prescription opioid abuse and dependence are a major public health concern. To explore alternatives to opioid-based analgesia, the present study investigates a novel allosteric pharmacological a...

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Detalles Bibliográficos
Autores principales: Lebovitz, Evan E, Keller, Jason M, Kominsky, Hal, Kaszas, Krisztian, Maric, Dragan, Iadarola, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556054/
https://www.ncbi.nlm.nih.gov/pubmed/22998799
http://dx.doi.org/10.1186/1744-8069-8-70

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556054/
https://www.ncbi.nlm.nih.gov/pubmed/22998799
http://dx.doi.org/10.1186/1744-8069-8-70

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