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Prediction of Structure of Human WNT-CRD (FZD) Complex for Computational Drug Repurposing
The observed genetic alterations of various extracellular and intracellular WNT (Wingless, Int-1 proto-oncogene) signaling components can result in an increase or decrease in gene expression, and hence can be obstructed proficiently. These genetics target sites may include the prevention of WNT-FZD...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556074/ https://www.ncbi.nlm.nih.gov/pubmed/23372744 http://dx.doi.org/10.1371/journal.pone.0054630 |