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Prediction of Structure of Human WNT-CRD (FZD) Complex for Computational Drug Repurposing

The observed genetic alterations of various extracellular and intracellular WNT (Wingless, Int-1 proto-oncogene) signaling components can result in an increase or decrease in gene expression, and hence can be obstructed proficiently. These genetics target sites may include the prevention of WNT-FZD...

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Detalles Bibliográficos
Autores principales: Ain, Qurrat U., Seemab, Umair, Rashid, Sajid, Nawaz, Muhammad Sulaman, Kamal, Mohammad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556074/
https://www.ncbi.nlm.nih.gov/pubmed/23372744
http://dx.doi.org/10.1371/journal.pone.0054630