Identification of GPCR-Interacting Cytosolic Proteins Using HDL Particles and Mass Spectrometry-Based Proteomic Approach

G protein-coupled receptors (GPCRs) have critical roles in various physiological and pathophysiological processes, and more than 40% of marketed drugs target GPCRs. Although the canonical downstream target of an agonist-activated GPCR is a G protein heterotrimer; there is a growing body of evidence...

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Detalles Bibliográficos
Autores principales: Chung, Ka Young, Day, Peter W., Vélez-Ruiz, Gisselle, Sunahara, Roger K., Kobilka, Brian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556083/
https://www.ncbi.nlm.nih.gov/pubmed/23372797
http://dx.doi.org/10.1371/journal.pone.0054942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556083/
https://www.ncbi.nlm.nih.gov/pubmed/23372797
http://dx.doi.org/10.1371/journal.pone.0054942

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