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TFPIα and TFPIβ are expressed at the surface of breast cancer cells and inhibit TF-FVIIa activity

BACKGROUND: Tissue factor (TF) pathway inhibitor-1 (TFPI) is expressed in several malignant tissues- and cell lines and we recently reported that it possesses anti-tumor effects in breast cancer cells, indicating a biological role of TFPI in cancer. The two main splice variants of TFPI; TFPIα and TF...

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Detalles Bibliográficos
Autores principales: Stavik, Benedicte, Tinholt, Mari, Sletten, Marit, Skretting, Grethe, Sandset, Per Morten, Iversen, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556101/
https://www.ncbi.nlm.nih.gov/pubmed/23320987
http://dx.doi.org/10.1186/1756-8722-6-5