APC/β-catenin-rich complexes at membrane protrusions regulate mammary tumor cell migration and mesenchymal morphology

BACKGROUND: The APC tumor suppressor is mutated or downregulated in many tumor types, and is prominently localized to punctate clusters at protrusion tips in migratory cells, such as in astrocytes where it has been implicated in directed cell motility. Although APC loss is considered an initiating e...

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Detalles Bibliográficos
Autores principales: Odenwald, Matthew A, Prosperi, Jenifer R, Goss, Kathleen H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556124/
https://www.ncbi.nlm.nih.gov/pubmed/23302090
http://dx.doi.org/10.1186/1471-2407-13-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556124/
https://www.ncbi.nlm.nih.gov/pubmed/23302090
http://dx.doi.org/10.1186/1471-2407-13-12

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